ill-disposed, malicious, opp. εὐήθης, Ar. Pax 822 (Comp., 823), D. 18.11, Pl. Ep. 360c, Ph. 1.529, etc.; of animals, κ. ὄρνεον καὶ πανοῦργον Arist. HA 613b23; esp. thinking evil, prone to put the worst construction on everything, Id. Rh. 1389b20; τὸ κακόηθες malice, wickedness, Pl. R. 401b, Men. 653, Ph. 1.684, etc. Adv., πανούργως καὶ -ήθως Men. Epit. 318; κ. πολιτεύεσθαι Philipp. ap. D. 18.78, cf. J. AJ 13.11.1: Comp. -εστέρως Poll. 4.148.
of things, infamous, abominable, κλειδία κρυπτὰ -έστατα Ar. Th. 422.
Medic., of sores, fevers, etc., malignant, Hp. Aph. 6.4, Prog. 20 (Sup.); ἐξάνθημα Phld. Ind.Sto. 26. Adv. -θως Hp. Art. 41 codd.